Norovirus is a substantial burden on the U.S. We compared norovirus outbreaks before and during COVID-19. There were fewer norovirus outbreaks during COVID-19 compared to a similar time period in 2019 (326 versus 638, P<0.001). CONCLUSION: COVID-19 public health interventions may be considered to decrease the burden of norovirus. This demonstrates the ability of more restrictive interventions to decrease other outbreaks of known or emerging viruses.