The focus of this book has been on estimating the budget impact when adding new drugs to the current mix of drug treatments. The components that need to be completed when estimating the budget impact of other types of health care interventions are the same, but the approach needed for each component may be different. In this chapter, we provide an overview of differences in approach needed for estimating the budget impact of new vaccines, diagnostic tests, surgical procedures, and devices. We also present examples of budget-impact analyses that have been performed for these types of health care interventions.